2,5-Dimethylbenzeneboronic acid

2,5-Dimethylbenzeneboronic acid - Names and Identifiers

Name	2,5-Dimethylbenzeneboronic acid
Synonyms	AKOS BRN-0086 AKOS BRN-0066 CHEMBRDG-BB 4003297 RARECHEM AH PB 0196 RARECHEM AH PB 0089 P-XYLENE-2-BORONIC ACID 2,5-DIMETHYLPHENYLBORONIC ACID 2,5-Dimethylphenylboronic acid 2,5-Dimethylbenzeneboronic acid Boronic acid, B-(2,5-dimethylphenyl)-
CAS	85199-06-0
InChI	InChI=1/C8H11BO2/c1-6-3-4-7(2)8(5-6)9(10)11/h3-5,10-11H,1-2H3

2,5-Dimethylbenzeneboronic acid - Physico-chemical Properties

Molecular Formula	C8H11BO2
Molar Mass	149.98
Density	1.07±0.1 g/cm3(Predicted)
Melting Point	186-191 °C (lit.)
Boling Point	305.1±52.0 °C(Predicted)
Flash Point	138.3°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.000367mmHg at 25°C
Appearance	Crystallization
Color	White
BRN	3241785
pKa	8.70±0.58(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.523
MDL	MFCD01863525

2,5-Dimethylbenzeneboronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
HS Code	29163990
Hazard Class	IRRITANT

2,5-Dimethylbenzeneboronic acid - Introduction

2,5-Dimethylbenzeneboronic acid is an organic compound with the chemical formula C8H11BO2. The following is a description of the nature, use, preparation and safety information of 2,5-Dimethylbenzeneboronic acid:

Nature:
-Appearance: 2,5-Dimethylbenzeneboronic acid is a colorless crystalline solid.
-Solubility: It is slightly soluble in water and more soluble in organic solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc.

Use:
- 2,5-Dimethylbenzeneboronic acid is an important organic synthesis intermediate, which can be used to synthesize biologically active molecules and drugs.
-It is often used as a catalyst for Suzuki-Miyaura reactions, which can be used to construct carbon-carbon bonds or carbon-heteroatom bonds.

Preparation Method:
- 2,5-Dimethylbenzeneboronic acid can be prepared by reacting phenylboronic acid with 2,5-dimethylphenyl bromide. The specific synthesis process involves organic synthesis technology and requires the use of appropriate protective measures and experimental equipment.

Safety Information:
- 2,5-Dimethylbenzeneboronic acid has low toxicity, but it is still necessary to follow appropriate laboratory operations and safety and health regulations.
-Avoid contact with skin and eyes during operation, and use respiratory protection equipment.
-When conducting experiments, operate in a well-ventilated environment to avoid inhaling dust or steam.
-When using and storing, keep it in a dry, cool place, away from fire and oxidizing agents.
-If exposed or inhaled, seek medical attention immediately and show your doctor safety information.

Last Update：2024-04-09 02:00:48